Clinical studies

COMPLETED PATIENT CLINICAL STUDIES

No.StartEndTitle (English)Title (Original)InstituteAuthor(s)CountryType of studyPathologyPrimary treated jointPatientsLanguagesPublication / Presentation
20
2006
2007
Use of Pulsed Signal Therapy for the treatment of pain and
functional limitation in the context of arthritic degenerative
pathology		Utilizzo della terapia a segnali pulsanti nel trattamento del
dolore e della limitazione funzionale nella patologia degenerativa
artrosica		Tor Vergata Policlinica, RomeDe Polo C, Trenca I, Frasca MG, Rocconi F? Zorbo S,
Santucci M, Caraccio V, Ceccobelli M, Lazzari M		Italy
Open LabelOsteoarthritisKnee, Hips 135IT ES EN
DE FR PT		Presented at 31° Congresso Nazionale AISD, Roma, 8-10
Maggio 2008
1920042005Pulsed Signal Therapy in degenerative arthritic pathology: our
experience		Terapia a segnali pulsanti nella patologia degenerativa
artrosica: nostra esperienza		Tor Vergata Policlinica, RomeRizzitano D., Gatti A., Croce C., Lazzari M., Guarino M.C.,
Martucci C., Limongi F., Caruso D., Proietti M., Lazzari M.		ItalyOpen Label OsteoarthritisKnee, Hips80IT ENPresented at 29° Congresso Nazionale AISD, Verona, 8-10
Giugno 2006
1820012001Efficacy of Pulsed Electromagnetic Fields in the treatment of
early osteoarthritis of the knee		Efficacy of Pulsed Electromagnetic Fields in the treatment of
early osteoarthritis of the knee		Changi General Hospital, SingaporeLim YW, Chong KC, Low COSingaporeDouble blindOsteoarthritis Knee41 ENPresented at the ECCEO 5, March 16 – 19, 2005, Rome
1719962001Permanent prospective study (VITAL)-Thru Mar 2001Permanent Prospective Study (VITAL) 1996 - 2001Ludwig Maximilian UniversityBreul, Hahn, RostGermanyOpen LabelOsteoarthritis Various42000 DEVarious
16 19992001Prospective Multicentric Study for the Treatment of
Osteoarthritis of the Knee Joint (Kellgren II and III) with Pulsed
Electromagnetic Signal Therapy		Prospektive multizentrische Studie zur Behandlung von
Gonarthrosen (Kellgren II und III) mit der Pulsierenden Signal
Therapie (PST)		Ludwig Maximilian University, MunichFaensen M., Breul R.GermanyOpen LabelGonarthrosis (grade II and
III)		Knee303DE ENOrthopadische Praxis 2001:11, pages 701-709.
Vortrag auf der 49. Jahrestagung der Vereinigung
Süddeutscher Orthopäden e.V. in Baden-Baden 2001.
1519971998Prospective, clinical verification study of PST in Gonarthrosis,
Coxarthrosis and degenerative LWS changes		Prospective, clinical verification study of PST® in Gonarthrosis,
Coxarthrosis and degenerative disorders of the lumbar spine.		PST Center MunichGumppenberg S. von, Martin H., Faensen M., Breul R.GermanyOpen LabelOsteoarthritisKnee, lower back148DE ENMedycyna sportowa, Dec. 1998, XIV(89): 31-34.
Presentation Norddeutsche Orthopädenvereinigung e. V.
48. Jahrestagung in Münster, June 1999.
Poster presentation 14. GOTS, June 1999, München.
1420012001Preliminary results of the treatment with Pulsed Signal Therapy
(PST) of osteochondral knee injuries		Risultati preliminari nel trattamento di lesioni osteocondrali di
ginocchio trattate con Pulsed Signal Therapy (P.S.T.		Universita degli Studi di Catania Di Martino M., Avondo S.,Russo T.C., Onesta M.G., Sessa
G.		ItalyOpen LabelOsteochondral injuriesKnee 15IT DE ENoffprint
1320002001The use of PST (Pulsed Signal Therapy) in osteo-arthritis of the
knee		Impiego della PST (Terapia a Segnale Pulsante) nell'artrosi del
ginocchio		Niguarda Hospital, MilanCossu M., Sias N., De Vito G.ItalyOpen LabelOsteoarthritisKnee 49IT DE ENLa Riabilitazione 2001: 34(4): pages 213-218
1219992000The use of Pulsed Signal Therapy (PST) in the treatment of
arthritis of the hand		Impiego della Terapia a Segnale Pulsante (PST) nell'artrosi della
mano		Niguarda Hospital, MilanLeuci C., Sias N,., Cossu M.ItalyOpen LabelOsteoarthritisHand21IT DE ENLa Riabilitazione 2000: 33(3): pages 109-14
1119981999Long-Term Results Achieved by Pulsed Signal Therapy (PST)Risultati a lungo termine della terapia a segnale pulsante (PST)Niguarda Hospital, MilanCossu M., Leuci C.ItalyOpen LabelOsteoarthritisKnee 34IT ENLa Riabilitazione 1999: 32(1): pages 11-15
1019981998PST (Pulsing Signal Therapy): a proposal for a chondroprotection with physical methodsLa PST (Terapia a Segnale Pulsante): proposta di condroprotezione con metodiche fisiche Niguarda Hospital, MilanCossu M., Portale N.ItalyOpen LabelOsteoarthritisKnee, Lower back 80IT ENLa Riabilitazione 1998: 31(2): pages 51-59
919971998Efficacy of pulsed electromagnetic therapy (PST) in painful knee
osteoarthritis		Etude de vérification de l'efficacité antalgique des champs
électromagnetiques pulsés (PST) dans la gonarthrose.		Cochin Hospital, ParisPerrot S., Marty M., Kahan A., Menkes C.J.FranceDouble blindOsteoarthritis Knee40EN DE FRArthritis Rheumatology 1998: 41(3); suppl. S357
Arthritis + Rheuma 2002:2, p. 101-104
Revue du Rheumatisme English Edition. 1998;11:715.
(abstract).
Presentation at National Scientific Meeting of the American
College of Rheumatology (ACR) - San Diego, CA, USA;
Nov. 8-12, 1998.
11th Presentation at 11th French Congress of
Rheumatology CNIT – Paris; France; Nov. 23-25, 1998.
819971998Pulsed Signal Therapy: Treatment Of Chronic Pain Due To
Traumatic Soft Tissue Injury		Pulsed Signal Therapy: Treatment Of Chronic Pain Due To
Traumatic Soft Tissue Injury		PST Clinic, VancouverHershler C., Sjaus A.CanadaOpen LabelTraumatic soft tissue
injury		Various Joints80ENInternational Medical Journal 1999: 6(3), offprint
05-0719901993Prospective Studies Using Extremely Low Frequency
electromagnetic Induction Therapy in the Treatment of Patients
with Inflammatory and Non-Inflammatory Arthritis		Prospective Studies Using Extremely Low Frequency
electromagnetic Induction Therapy in the Treatment of Patients
with Inflammatory and Non-Inflammatory Arthritis		Three Yale University Clinical Cnters, Yale
University, School of Medicine teaching
Hospital		Trock D.H., Roseff R., Spiegel M, Heller E., Higley R. M.
Dyer R.H., Miner W. K, DeWitt S. H.
Greco T.P., Markoll R.		USAOpen LabelInflamattory and noninflammatory arthritis extremity joints & spine (cervical or
lumbar)

Knee, hip

Knee, shoulder,
cervical, dorsal &
lumbar spine		38

97

69		ENextracts from protocols and results
419911993The effect of pulsed electromagnetic fields in the treatment of
osteoarthritis of the knee and cervical spine		The effect of pulsed electromagnetic fields in the treatment of
osteoarthritis of the knee and cervical spine		Three trial centers: Waterbury, Danbury,
Melville		Trock D.H., Roseff R., Spiegel M, Heller E., Higley R. M.
Bollet A.J., Markoll R.		USADouble blindOsteoarthritisCervical Spine 81 DE ENJournal of Rheumatology 1994; 21: 1903-11
319911992The Effect of Pulsed Electromagnetic Fields in the Treatment of
Osteoarthritis of the Knee and Cervical Spine		The Effect of Pulsed Electromagnetic Fields in the Treatment of
Osteoarthritis of the Knee and Cervical Spine		Three trial centers: Waterbury, Danbury,
Melville		Trock D.H., Roseff R., Spiegel M, Heller E., Higley R. M.
Bollet A.J., Markoll R		USADouble blindOsteoarthritisKnee 86 DE ENJournal of Rheumatology 1994; 21: 1903-11
219901991A double-blind trial of the clinical effects of Pulsed
Electromagnetic Fields in Osteoarthritis		A double-blind trial of the clinical effects of Pulsed
Electromagnetic Fields in Osteoarthritis		Yale University School of Medicine teaching
Hospital Waterbury, Connecticut		Greco T.P., Markoll R.USADouble blindOsteoarthritisextremity joints
(knees), cervial, dorsal,
lumbar spine		47 DE ENstudy data available upon request
119901991A Double-Blind trial of the Clinical Effects of Pulsed
Electromagnetic Fields in Osteoarthritis		A Double-Blind trial of the Clinical Effects of Pulsed
Electromagnetic Fields in Osteoarthritis		Yale University School of Medicine teaching
Hospital Waterbury, Connecticut		Trock D.H., Bollet A.J., Dyer R.H., Fielding L.P., Miner
W.K., Markoll R.		USADouble blindOsteoarthritis Knee 27 EN DEJournal of Rheumatology 1993: 20(3): 456-460

COMPLETED IN VITRO STUDIES

No.StartEndTitle (English)Title (Original)InstituteAuthor(s)CountryPublication / Presentation
4
2001
2001
Effects of Pulsed Signal Therapy on 3-dimensional
Chondrocyte Culture
Die Wirkung der Pulsierenden Signal Therapie auf
eine dreidimensionale Chondrozytenkultur
Charité - Humboldt Universität, Berlin
Krüger I., Faensen M., Zimmermann J.,
Knedel T., Sittiger M.
Germany
Presentation at the 1st Biennial Meeting Tissue Engineering Society
(ETES)-2001 Symposium of the International Cartilage repair
sciety (ICRS)-Freiburg Germany Nov 7-10, 2001
320002000Pulsed Signal Therapy (PST) Stimulates Mitosis of Human
Chondrocytes In Culture		Pulsed Signal Therapy (PST) Stimulates Mitosis of
Human Chondrocytes In Culture		Praxis für Orthopädie und Sportstraumatologie,
Köln		Gierse H., Breul R., Faensen M., Markoll R.GermanyPresentation at the Deutsches PST Symposium, Salzburg, austria,
May 19, 2001.
220002000Biochemical and morphological study of human articular
chondrocytes cultivated in the presence of pulsed signal
therapy		Biochemical and morphological study of human
articular chondrocytes cultivated in the presence of
pulsed signal therapy		Institute of Rheumatology, University of SienaNerucci F., Marcolongo R., Markoll R.,
Fioravanti A., G. Collodel.		ItalyAnnals of the Rheumatic diseases, nov. 2002, Vol 61, no. 11, p 1032-
1033.
Presentation at Bioelectrics Magnetic Society (BEMS) 22nd
meeting Annual Abstract book, Munich, Germany June 11-16 2000,
page 48
119921992The stimulation of chondrocyte metabolism by pulsed
magnetic fields		The stimulation of chondrocyte metabolism by pulsed
magnetic fields		North Shore University Hospital, USAGrande D.A.,Bollet A.J., Markoll R. USAmanuscript

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